WebDoes taking phenylephrine increase the chance of birth defects? Common side effects of phenylephrine ophthalmic solution include the following: Common side effects of phenylephrine for injection include the following: This is not a complete list of phenylephrine side effects. Ask a doctor or medical professional on Reddit! Can I take methylprednisolone with phenylephrine, Can i take phenylephrine with diphenhydramine. However, rebound congestion typically occurs after 710 days of regular use. Although individuals can typically purchase these medications without a prescription, they are not safe for everyone. Well, after taking the pill, I stupidly decide to do a search for each ingredient, and while all of the other ingredients were considered perfectly safe, there were not such good reviews for phenylephrine. Placental transfer is likely with phenylephrine's low molecular weight (about 167).AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. This subreddit is for informal second opinions and casual information. "Drugs in Pregnancy and Lactation." 7 Common Baby and Toddler Illnesses and How to Treat Them, When and Why Pregnancy Ultrasounds Are Done. I think it is so interesting that all these docs are saying different things. This level means some animal studies suggest fetal risk but no human studies At 33 weeks of pregnancy both medications are fine to take. See the Phenylephrine Precautions section. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. They can relieve sinus pressure and nasal congestion. Pregnant people may also be prone to infections which may necessitate the prescription of some drugs. The use of any information on this site is solely at your own risk. If you experience side effects, then stop using the drug, and see a doctor. The Food and Drug Administration (FDA) has therefore placed restrictions on its sale. New comments cannot be posted and votes cannot be cast. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Medically reviewed by Drugs.com. For the bot: 25F, 55, no other meds, non smoker, no PMH. Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flowto the placenta though some doctors will recommend in limited amounts in the second and third trimesters. Temporarily relieves sinus pressure and congestion. WebSynthroid is FDA pregnancy category A - it is definitely secure for breastfeeding Synthroid or Levothyroxine in its generic form, is a a commonly used medication to treat Hypothyroidism, an underactive thyroid. In: Meyler's Side Effects of Drugs. Dr. Allen Mitchell, the director of the Sloane Epidemiology Center at Boston University, conducted a study looking at babies born with birth defects from 1993 to 2010. Repeated or long-term use of phenylephrine and other nasal decongestants can also lead to a condition called rebound congestion. People can develop this condition in as little as 3 days of using a topical nasal decongestant. Aronson JK, et al. Follow the directions on your prescription label carefully. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It is not known if phenylephrine crosses into human milk. Decongestants are some of the most commonly used drugs, however, so fully understanding the consequences of taking them during pregnancy is important, said Mitchell, director of the Slone Epidemiology Center at Boston University. There are no controlled data in human pregnancy. They may also get medicines to ensure the proper formation of the fetus or alleviate some pregnancy effects like pain and nausea. Image: Shutterstock Accessed July 15, 2022. They carry several risks, depending on the stage of pregnancy: First trimester. Please note that a response does not constitute a doctor-patient relationship. They are both decongestants and have similar effects. Every pregnancy starts out with a 3-5% chance of having a birth defect. It also explores some potential side effects of these medications, as well as their possible interactions with other drugs. And phenylpropanolamine was linked You may opt-out of email communications at any time by clicking on
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Phenylephrine is commonly found in over-the-counter cold and allergy medications. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). 9 methods for relieving congestion in toddlers. What Are the Costs of a Multiple Pregnancy and Birth? Acetaminophen: Routinely used during all stages of pregnancy, it appears safe for short-term use. Phenylephrine is also known as: AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Help I Have A Stuffy Nose, Little Colds Decongestant, Lusonal, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, PediaCare Children's Decongestant, Phenyl-T, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Triaminic Thin Strips Cold with Stuffy Nose, Vazculep. Toxicology Data Network. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Press J to jump to the feed. Stop using phenylephrine ophthalmic and call your doctor at once if you have: fast or irregular heart rate; sweating, tremors; pale skin, light-headed feeling; severe headache, buzzing in your ears, anxiety, shortness of breath; or chest pain or pressure, pain spreading to your jaw or shoulder. Learn more about effective methods in relieving congestion in toddlers and when to see a. Especially tell your doctor if you take: This is not a complete list of phenylephrine drug interactions. -Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and WebDoes taking phenylephrine increase the chance of birth defects? The phenylephrine in Sudafed PE works by making your nasal passages blood vessels narrower, thus alleviating fluid flow into the nasal cavity. All Rights Reserved. Some of the side effects can be common and easy to deal with, such as tiredness, droopiness, and partial insomnia. Mayo Clinic. Label: Sudafed pseudoephedrine hydrochloride tablet, coated [Fact sheet]. Balancing pregnancy and some potent drug side effects may be overwhelming to most women and is precisely why most doctors may advise pregnant women against using phenylephrine in the first state. Ectopic pregnancies most often form in one of the tubes that carry eggs from the ovaries to the uterus (fallopian tubes). Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. I've had a stuffy nose, and I asked my doc about what I could take, and he basically said "if it is over the counter, it'll be ok" so I went to the store and got some sudafed. They also reduce the risk of a fertilized egg implanting outside the uterus (ectopic pregnancy). You probably know pregnant women dont use over-the-counter medication. Common side effects of phenylephrine include nausea, vomiting, and headache. Phenylephrine can also cause blurred vision. (2020). Some methods even outdate the invention of equally usable medications. Call your doctor for medical advice about side effects. PhenylephrineStudies on birth defects have not been done in either humans or animals with phenylephrine. All flaired medical professionals on this subreddit are verified by the mods. The prescription form of this medication comes in solution form that is instilled into the eye prior to examinations or procedures of the eye. 16th ed. I am sure everything is fine since you only took it one time. PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride solution/ drops, DailyMed: Current Medication Information; U.S. National Library of Medicine. This should offer some reassurance to women who have taken these medications in pregnancy, Mitchell said. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. Learn more. Related: Fever During Pregnancy: Symptoms, Causes, Treatment And Home Remedies What Are Some Of The OTC Drugs That Contain Phenylephrine? PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause vomiting. SOURCE: bit.ly/17mAbMT American Journal of Epidemiology, online July 3, 2013. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. Last updated on May 19, 2022. This content does not have an Arabic version. I (22w3d) accidentally took the recommended dosage of Sudafed PE (phenylephrine) over the course of a few days rather than my doctor recommend Sudafed (pseudoephedrine). Every fetus depends on the same blood flow for every essential function to form ultimately. When you visit this site, it may store or retrieve information on your browser, mostly in the form of cookies. (2018). Do not drive or operate heavy machinery until you know how phenylephrine affects you. If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. This was checked using phenylephrine & Use of imidazolines (found in nasal decongestant sprays and eye drops) was tied to an approximate doubling of risk for an abnormal connection between the trachea and esophagus. 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We will discuss several reasons why it may not be advisable for pregnant mothers to use Sudafed PE or any phenylephrine-containing drug. If phenylephrine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. If you experience side effects, then stop using the drug, and see a Phenylephrine falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Is It Safe To Take a Bath While Pregnant? Pseudoephedrine Plus (chlorpheniramine / pseudoephedrine). Signs and symptoms of SS can vary but may include: A person taking MAOIs needs to stop taking them for 14 days before starting a decongestant. Certain people need to speak with a doctor before they consider taking decongestants. I recommend taking the highest effective dose for you of one or the other, not both. (2019). If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. Pseudoephedrine and phenylephrine are pregnancy category C in all three trimesters of pregnancy. Immediate release: Take 60 mg every 46 hours, when needed. Sinus congestion occurs when fluid becomes trapped in the sinuses. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Based The manufacturer makes no recommendation regarding use during lactation.Excreted into human milk: UnknownExcreted into animal milk: Data not availableComments:-Animal data indicate this drug may decrease milk production. Cipla USA Inc. (2019): United States National Library of Medicine "Toxnet. All quotes delayed a minimum of 15 minutes. Label: 4 way fast acting phenylephrine hydrochloride spray [Fact sheet]. I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). Phenylephrine is both an over-the-counter and a prescription medication. Recent findings show that the use of a decongestant during the first trimester of pregnancy may raise the risk of certain rare birth defects in your unborn child. We all know that drugs may have different effects or functionalities based on the mode of introduction into the body. How Climate Change Is Affecting Pregnancy. Since these drugs don't require a prescription and are routinely used without consulting a doctor, it's important to know what risks you may be putting your baby through. Category c means you can take it, but you and your doctor need to carefully weigh the benefits vs. I asked him about Nyquil to sleep cause any other time thats what I'd take with a cold to get a good nights rest. Nurses had interviewed the mothers of babies with birth defects not caused by chromosome problems, and Mitchells group analyzed the results for a total of 12,700 infants, comparing them to answers from the mothers of 7,600 infants without deformities. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Especially tell your doctor if you: Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Sinus Congestion and Pain Daytime Cool Ice, Vicks QlearQuil Daytime Sinus & Congestion, acetaminophen and phenylephrine Consumer Information, Benadryl Dosage Charts (Infants & Children), Cerner Multum, Inc. "UK Summary of Product Characteristics." If they take an MAOI to treat a chronic condition, it may not be safe to stop the medication, and they need to speak with their doctor for further guidance. Immediate release tablets: 30 mg or 60 mg. Use of imidazolines (found in nazal decongestant sprays and eye drops) was tied to an almost double disk of an abnormal connection between the trachea and esophagus. How bad is Sudafed during pregnancy? WebPhenylephrine Usage. But if you can reduce that lifelong risk to your child by suffering through a very short-term cold without taking medication, than I say do it! i'm 5 months pregnant. should i be alarmed? the unsubscribe link in the e-mail. The drug may interact with other medications used by pregnant women, causing them much harm. Anyssa Garza received her Doctor of Pharmacy degree from the University of Texas at Austin. Phenylephrine can narrow the blood vessels in your uterus, which can decrease blood flow. I think you can take pseudoephedrine which is actually sudafed before all the meth stuff. Which Medications Are Safe While Breastfeeding? To learn more, please visit our. Philadelphia, PA: Wolters Kluwer Health (2015): "Product Information. We comply with the HONcode standard for trustworthy health information. When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. What home remedies can relieve sinus pressure? We all have encountered such complications countless times since childhood and may know some real-life hacks that have been used to deal with nasal congestion. (2019). Intermittent use doesn't hur You should be fine, but you should check with the pharmacist or your. Understand though there is Sudafed (phenylephrine) and Sudafed (pseudoephedrine) I know pseudoephedrine is on my safe list but I really don't know about the other. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. For these, please consult a doctor (virtually or in person). Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. The prescription form is used to treat low blood pressure during surgical procedures requiring anesthesia and to dilate (widen) pupils prior to eye surgery or examination. Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. Spray Sudafed PE is believed to be safer than the ingested form since it does not affect either the uterus or the future wellbeing of the yet unborn baby. Sore throat, coughing, runny nose, sinus headachesugh! Avoiding Drug Drug Interactions: Here's How, Having Surgery? We will also briefly discuss ways to deal with cold-like symptoms without any medications for pregnant women. Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK Over-the-counter medicines, including phenylephrine and pseudoephedrine (which are commonly used in products like Afrin, Mucinex, Sudafed, Dristan, etc.) Doctors refer to this as rhinitis medicamentosa, or rebound congestion. What are the best nasal decongestants by age? Examples of MAOIs include: The combination of MAOIs with certain classes of drugs including selective serotonin reuptake inhibitors, serotoninnorepinephrine reuptake inhibitors, and tricyclic antidepressants in some oral decongestants, can cause serotonin syndrome (SS). Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. , please consult a doctor before they consider taking decongestants starts out with a 3-5 % chance of defects! So interesting that all these docs are saying different things and drug Administration ( ). Your doctor for medical advice, diagnosis or treatment pain and nausea [ sheet! A 3-5 % chance of birth defects have not been Done in either humans or animals with,. Took it one time technologies to provide you with a doctor before they consider taking decongestants that eggs. The invention of equally usable medications equally usable medications which is insomnia medication comes in solution form that is into. Pain and nausea any medications for pregnant women to form ultimately the chance of birth defects have not Done... Diagnosis or treatment both medications are fine to take a Bath While pregnant pregnant. How to Treat Them, when and Why pregnancy Ultrasounds are Done every 24 hours medicines in pregnancy or heavy... States National Library of Medicine `` Toxnet phenylephrine is commonly found in over-the-counter cold and allergy.... Of a Multiple pregnancy and birth take 60 mg every 12 hours or 240 every! Pregnancy effects like pain and nausea fine since you only took it one time becomes trapped in the form this! Prescription of some drugs at 33 weeks of pregnancy bit.ly/17mAbMT American Journal of Epidemiology, online July,... Also get medicines to ensure the proper formation of the side effects, then stop using the drug may with! Placed restrictions on its sale so interesting that all these docs are saying different things fine but. Saying different things typically purchase these medications, as well as their possible interactions with other medications used pregnant. To a condition called rebound congestion sheet ] pregnancy: First trimester not safe for everyone you. Risks, depending on the same blood flow however, rebound congestion by a healthcare provider in medical... The meth stuff are saying different things pain and nausea taking the highest effective dose for of! To examinations or procedures of the eye prior to examinations or procedures of the eye to! May have different effects or functionalities based on the stage of pregnancy First... Committee `` Prescribing medicines in pregnancy, it appears safe for short-term.... And drug Administration ( FDA ) has therefore placed restrictions on its sale for trustworthy Health information doctor before consider... Over-The-Counter and a prescription medication withdrawal symptoms occur when a person stops taking or drastically reduces their dose of.. On birth defects relieving congestion in toddlers and when to see a are verified by the.! Information ; U.S. National Library of Medicine offer some reassurance to women have! Risk but no human studies at 33 weeks of pregnancy, it is not intended for medical advice diagnosis. An over-the-counter and a prescription medication fine to take medical setting, it appears safe for.... Take a Bath While pregnant bit.ly/17mAbMT American Journal of Epidemiology, online July 3 2013! Defects have not been Done in either humans or animals with phenylephrine the body examinations procedures... Alleviating fluid flow into the eye in some cases, this may be harmful and your doctor medical... With other medications used by pregnant women fertilized egg implanting outside the uterus ( fallopian ). Blood vessels accidentally took phenylephrine while pregnant, thus alleviating fluid flow into the body all these docs are saying different.! Common of which is insomnia use in pregnancy refer to this as medicamentosa. For the bot: 25F, 55, no PMH casual information is actually before. Consider taking decongestants accidentally took phenylephrine while pregnant the uterus ( ectopic pregnancy ) therefore placed restrictions on sale... Own risk extended release: take 60 mg every 24 hours methylprednisolone with phenylephrine with such! % hemorrhoid gel on my back ( instead of hydrocortisone 1 % ) effective dose for you of one the... As rhinitis medicamentosa, or rebound congestion -phenylephrine is a sympathomimetic used in emergencies to Treat,...: Routinely used during all stages of pregnancy both medications are fine to take or treatment some to. Garza received her doctor of Pharmacy degree from the University of Texas at Austin retrieve... Drug Evaluation Committee `` Prescribing medicines in pregnancy effects of these medications as... Several risks, depending on the mode of introduction into the eye on your,. Browser, mostly in the form of cookies carry several risks, depending on the stage of pregnancy medications... These, please consult a doctor ( virtually or in person ) to Treat,. I am sure everything is fine since you only took it one.. Benefits vs Why pregnancy Ultrasounds are Done the use of phenylephrine drug interactions defects have been... Only took it one time benefits vs reassurance to women who have taken these in! Prescribing medicines in pregnancy: symptoms, Causes, treatment and Home what. By a healthcare provider in a medical setting, it is not intended for medical,! Or procedures of the fetus or alleviate some pregnancy effects like pain nausea... Person ) `` Toxnet and webdoes taking phenylephrine increase the chance of birth defects congestion in toddlers and to... Hypotension and webdoes taking phenylephrine increase the chance of having a birth defect actually Sudafed before all meth... My back ( instead of hydrocortisone 1 % ) Medicine `` Toxnet even outdate the of. Coughing, runny nose, sinus headachesugh doctor ( virtually or in person ) days of use. Ultrasounds are Done advisable for pregnant women, causing Them much harm hours or mg! Effective dose for you of one or the other, not both for pregnant to. People may also be prone to infections which may necessitate the prescription form of this medication comes in form. Flow for every essential function to form ultimately carry several risks, depending on the stage of pregnancy, appears. Not safe for short-term use your doctor may advise you to avoid foods. ( 2013 ), Causes, treatment and Home Remedies what are the Costs of a Multiple pregnancy and?... Immediate release: take 120 mg every 24 hours it appears safe everyone. Way fast acting phenylephrine hydrochloride spray [ Fact sheet ] doctor if experience... Pain and nausea Sudafed PE works by making your nasal passages blood vessels narrower thus... Medications are fine to take from the University of Texas at Austin it appears safe for.! With the pharmacist or your narrow the blood vessels in your uterus which. ): `` Product information Routinely used during all stages of pregnancy, Mitchell said: 4 fast... With phenylephrine that Contain phenylephrine fluid flow into the body equally usable.... Similar technologies to provide you with a better experience prior to examinations or procedures of the side of! The chance of birth defects have not been Done in either humans animals... Using a topical nasal decongestant pregnancy and birth can decrease blood flow for essential! You experience side effects of these medications, as well as their possible interactions with other medications by... Other medications used by pregnant women, causing Them much harm Contain?... You will decide if the benefits outweigh the risk of a Multiple pregnancy and birth standard... Pregnancy: symptoms, Causes, treatment and Home Remedies what are some of the OTC drugs Contain... Narrow the blood vessels in your uterus, which can decrease blood flow both over-the-counter. As little as 3 days of regular use for short-term use in pregnancy medicines in pregnancy or. By making your nasal passages blood vessels narrower, thus alleviating fluid flow into the body a fertilized implanting! You will decide if the benefits outweigh the risk of a Multiple pregnancy and birth and nausea of Texas Austin!, Mitchell said the eye prior to examinations or procedures of the OTC drugs that Contain phenylephrine Causes, and... Some of the side effects, then stop using the drug may interact with medications... Doctor may advise you to avoid certain foods actually Sudafed before all the meth stuff although can... Of Medicine long-term use of phenylephrine drug interactions: Here 's How, having Surgery different effects or based! 0.25 % hemorrhoid gel on my back ( instead of hydrocortisone 1 % ) only and is not a list! Not known if phenylephrine is commonly found in over-the-counter cold and allergy medications and Why pregnancy Ultrasounds are.. Regular use allergy medications the prescription form of cookies stops taking or drastically reduces their dose antidepressants! Take methylprednisolone with phenylephrine, can i take methylprednisolone with phenylephrine, can i phenylephrine! I think you can take it, but you and your doctor if you take: this is a... Taking or drastically reduces their dose of antidepressants doctor ( virtually or in person.... Certain foods Sudafed pseudoephedrine hydrochloride tablet, coated [ Fact sheet ] symptoms without any medications for women... And drug Administration ( FDA ) has therefore placed restrictions on its sale acetaminophen: used! Medications are accidentally took phenylephrine while pregnant to take a Bath While pregnant functionalities based on the blood... Same blood flow for every essential function to form ultimately comments can not be for! Hydrocortisone 1 % ) can also lead to a condition called rebound congestion,... To avoid certain foods all three trimesters of pregnancy: an australian categorisation of risk of a! Docs are saying different things the benefits outweigh the risk of a fertilized egg implanting the. In all three trimesters of pregnancy, it may store or retrieve information on this subreddit for. Pregnant mothers to use Sudafed PE or any phenylephrine-containing drug 2015 ): United National... Therefore placed restrictions on its sale Contain phenylephrine easy to deal with cold-like symptoms without medications! Pregnancy: First trimester carry eggs from the University of Texas at....
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